By Emel Gerdaneri • Medical review by Mutlu Adiguzel, MD on September 30, 2022

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It is the result of a mesotherapy performed by Sevgi Ekiyor, MD. For reference purposes only, results may vary.

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Mesotherapy is a cosmetic procedure that involves injecting of a mixture of vitamins, minerals, medications, and other substances directly into the middle layer of the skin to improve the appearance of the skin and reduce the signs of aging.

Mesotherapy is performed with a very fine needle. The treatment plan is unique and customized according to the individuals needings.

Mesotherapy treatments are used for to address a variety of skin concerns, (including wrinkles, fine lines, pigmentation, and acne scars), rejuvenate the skin, reduce cellulite, promote weight loss and treat localized fat deposits. 

The content of the injections changes due to the target therapy. The injections may include ingredients such as hyaluronic acid, vitamins, antioxidants, amino acids, enzymes, hormones, and plant extracts.

Mesotherapy is generally considered a safe procedure. However, like any medical procedure, there are some potential side effects, such as bruising, swelling, and discomfort at the injection site. In rare cases, infection or allergic reaction can occur.

Additionally, mesotherapy is not recommended for everyone. People with certain medical conditions or taking certain medications may be at increased risk of complications.

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The right candidates for mesotherapy are generally people (both male&female) who is in good overall health and has realistic expectations for the results of the procedure. The candidates must be between the ages 16 years -75 years.

Mesotherapy is generally not recommended for people who are pregnant or breastfeeding, or who have certain medical conditions such as diabetes or autoimmune diseases.


In General the people who has the cosmetic and health problems listed below are the right candidates for Mesotherapy:

Individuals who have; 

  • Regional lubrication,

  • Hair loss,

  • Cellulite and stretch marks problem,

  • Aging process with sagging and wrinkle problems,

  • Acne and acne scar problems are ideal candidates for Mesotherapy treatment.

Mesotherapy method is also performed in the treatment of some health problems.

  • Migraine,

  • Neck and lumbar hernia patients,

  • People who experience severe menstrual pain before and during the menstruation period,

  • Have the problem of varicose and varicose ulcers

Mesotherapy is typically performed as an outpatient procedure, meaning patients can go home the same day. The procedure usually takes less than an hour to complete, depending on the size and location of the targeted area.

Generally, 2-3 sessions of treatments are needed for the treatment process of each problem. All the mesotherapy treatments are performed under local anesthesia.
Hair Loss Treatment with Mesotherapy:

During the Hair Loss Treatment with Mesotherapy, the solution is prepared due to the patient's needs and the cause of their hair loss and will directly inject the into the scalp.

Common ingredients used in hair loss mesotherapy solutions include biotin, vitamins B and C, zinc, copper, and amino acids. The procedure typically takes less than an hour to complete, and patients can return to their normal activities immediately afterward.

However, multiple sessions may be required for optimal results, usually scheduled a few weeks apart.

Cellulite Treatment with Mesotherapy

Cellulite treatment with mesotherapy is performed by the injections prepared with a mixture of vitamins, minerals, and medications directly into the affected area of skin.

The ingredients in the solution may include caffeine, aminophylline, hyaluronic acid, and enzymes that break down fat cells.

The Cellulite treatment with mesotherapy is based on the theory of breaking down fat cells and improve blood flow, leading to a reduction in the appearance of cellulite.

mesotherapy -3

Skin Rejuvenation with Mesotherapy

Mesotherapy is a popular cosmetic treatment for skin rejuvenation. During a skin rejuvenation treatment session with mesotherapy, the healthcare provider will inject a customized mixture of vitamins, minerals, and other substances directly into the middle layer of the skin (mesoderm).

The ingredients in the solution may include hyaluronic acid, vitamins A, C, and E, amino acids, and antioxidants.

Mesotherapy for skin rejuvenation is based on the theory of improving skin texture and tone, and reduce the appearance of fine lines and wrinkles, with the help of a  customized solution, that will stimulate collagen production.

Spot Treatment with Mesotherapy

Mesotherapy can also be used as a spot treatment for specific skin concerns, such as acne scars, dark spots, and fine lines.

During a spot treatment session with mesotherapy, a customized mixture of vitamins, minerals, and other substances will directly injected into the targeted area.

The procedure may take less than an hour to complete. Multiple sessions may be required for optimal results, usually scheduled a few weeks apart.

Mesotherapy for spot treatment is based on the theory of improving the targeted concern by stimulating collagen production, reducing inflammation, and delivering targeted nutrients to the area.

Regional fat Burn with Mesotherapy

Mesotherapy can also be used for regional fat burning, particularly for small areas of fat that are resistant to diet and exercise.

During a regional fat burning treatment session a customized mixture of fat-dissolving substances, such as phosphatidylcholine and deoxycholate, will directly injected into the targeted area.

The ingredients in the solution work to break down and dissolve fat cells, which are then eliminated from the body through natural processes.

Mesotherapy for regional fat burning is based on the theory of break down and dissolve fat cells, by the help of the injection of the customized solution.


  • Mesotherapy is a customizable treatment that can be tailored to each individual patient's needs,

  • Mesotherapy is a non-surgical treatment that can be performed on an outpatient basis,

  • Mesotherapy treatment have no downtime or recovery period,

  • Mesotherapy can be used for a variety of cosmetic concerns, including skin rejuvenation, hair loss, cellulite reduction, and regional fat burning,

  • Mesotherapy is generally well-tolerated, with minimal side effects reported in most cases.



  • The long-term effects of the Mesotherapy are not well known.

  • As with any injection-based treatment, there is a risk of infection, bruising, bleeding, and other complications associated with mesotherapy.

  • Mesotherapy can be expensive, particularly if multiple sessions are required to achieve the desired results.

  • While mesotherapy can offer noticeable improvements in skin texture, hair growth, and other cosmetic concerns, results can vary widely between patients and are not guaranteed.

The cost of mesotherapy can vary depending on several factors, such as the number of treatment sessions required, the healthcare provider performing the treatment, and the geographic location of the clinic or medical center.

In general, mesotherapy treatments can cost anywhere from a few hundred to a few thousand dollars per session, with multiple sessions typically required for optimal results.

For example, a single session of mesotherapy for hair loss may cost between $250 to $500, while a session for skin rejuvenation may range from $400 to $800.

A mesotherapy treatment starts by cleaning and preparing the treatment area.

A topical anesthetic cream will be applied to help minimize any discomfort during the injection process.


Depending on the area that will be treated, a specialized mixture of vitamins, minerals, medications, and other substances injection will be prepared and the healthcare provider will then use a fine needle to inject directly into the middle layer of the skin or fat layer.

After the injection, to reduce the risk of bruising or swelling, the provider may massage the area.

After mesotherapy, most of the individuals can return back to their normal activities immediately while some individuals experience some mild side effects, including redness, swelling, bruising, tenderness, and itching at the injection sites.

The side effects after mesotherapy are usually mild and resolve on their own within a few days. Some patients may also experience minor skin peeling or flaking depending on the area treated and the specific substances used.

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After mesotherapy sessions are over patients may begin to expect to see the results within a few days or weeks after their first mesotherapy treatment. The most noticeable improvements typically seen after several treatment sessions.

In general, mesotherapy results lasts starting from several months to a year or more. The duration of mesotherapy results can vary according to the individuals lifestyle and skincare routine. Mesotherapy results are not permanent.

There are several alternatives to mesotherapy. Some of these options include:

  • Topical treatments which contains retinoids, vitamin C, or hyaluronic acid,

  • Chemical peels for to treat acne, fine lines, and hyperpigmentation.

  • Laser treatments for to resurfacing or skin rejuvenation treatments. 

  • PRP therapy for to treat fine lines, wrinkles, and hair loss.

  • Botox and dermal fillers for to smooth wrinkles, add volume, and improve the overall appearance of the skin.

Written on 15/05/2017


Last Update: 20/10/2023

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